If your response to Orlando is...
...to call for more guns, or talk about how "if only they were armed": consider what you are saying, and don't just parrot the same old party line regardless of the circumstance. Because let's be clear, these circumstances are not "more guns" circumstances. When people are partying, dancing, relaxing and hanging out in a club, they don't need a bunch of partygoers packing heat. Alcohol and firearms are a lethal combination, not a solution. This is just another problem proposed as a solution.
...to congratulate yourself that your particular brand of bigotry doesn't involve murdering gay people: fuck you. Seriously. Isolating, harassing and persecuting people, or fighting to make it legal to do so, doesn't make you a good guy. You may not personally be murderously inclined, but when you contribute to a culture that drives gay kids to suicide all the time...guess what? You've got blood on your hands. When you contribute to a culture that demonizes, harasses and persecutes gay people, you don't get a free pass just because there's someone out there who is worse than you. And fuck you for even going there.
...blame all gun owners: stop. Seriously. You're not helping anything. You're alienating millions of people who would not hurt a fly, and feeding right into the NRA's "liberals want to take out guns" BS. Don't lash out at people for utilizing a constitutional right. Contribute to finding the solution, not making noise.
...saying this has nothing to do with Islam: listen to the shooter, and stop talking. No, of course this isn't the fault of other Muslims. And maybe the shooter was a bad Muslim. Certainly there were other factors at play too. But when someone is vocally mowing people down for their god, why the hell would you deny that reality? You won't stop bigotry that way; you're just throwing your weight onto a demonstrably false point.
...blame all Muslims: piss off. Unless you are willing to assign the blame for Robert Lewis Dear, Westboro, the KKK, etc, on all Christians, you're a hypocrite; and if you are, you're just wrong. There's certainly things the Muslim community can do to combat homophobia, and those are legitimate points to make. But if you are using this as an opportunity to dump on Muslims and hold them to standards you won't hold yourself to...again, piss off.
...suggest banning people on the terror watch list from weapon purchases: think through what you're asking for. This one sounds like a good one on the surface, but it really isn't. You're suggesting that *suspicion* should be enough to deprive someone of their constitutional rights. Again, these aren't people who have been proved to be doing harm, they're not people who have been charged with crimes. These are people *suspected* of terrorist leanings. Our constitutional rights should never be waved over suspicion.